Alcohol
Alcohol kills bacteria too, that’s why it’s an effective disinfectant. When you consume alcohol, it takes some time to break down. In the meantime, it kills gut bacteria unbalancing your digestive system.
Try to keep alcohol intake at a minimum, or at the very least try not to drink more than two beverages per hour. That way, your body will have plenty of time to absorb the alcohol before it damages your gut bacteria.